Derek J. Chadwick

The formation of blood vessels is an essential aspect of embryogenesis in vertebrates. It is a central feature of numerous post-embryonic processes, including tissue and organ growth and regeneration. It is also part of the pathology of tumour format…

Gramicidin channels have been studied intensively for more than 25 years. They serve as model transport systems for large protein ion channels, since it is difficult to glean high-resolution structural information on the latter. This book includes co…

As part of a continuing effort to tackle issues of major social concern, this 280th conference of internationally recognized experts from the fields of molecular biology, medicine, philosophy, theology, and the law looks into the scientific, legal, e…

The book presents recent advances relating to the factors and mechanisms that regulate the growth, differentiation and function of mast cells and basophils; discussion of new technologies used to study these cells, and integration of the basic scient…

Asthma is a growing health problem throughout the developed world. This volume presents a critical review of all the possible factors for this rising trend and includes research that has not yet been published in the scientific literature. Discusses …

The heat shock, or cell stress, response was first identified in the polytene chromosomes of Drosophila. This was later related to the appearance of novel proteins within stressed cells, and the key signal stimulating this appearance was identified a…

Smooth muscle contraction is a vital component of the functioning of blood vessels, the uterus, airways and the bladder. Its malfunction can lead to serious pathological conditions, such as hypertension and pre-term labour. The calcium ion plays a ce…

Microbial responses to acidic and alkaline pH are important in many areas of bacteriology. For example, the mechanisms of resistance to acidic pH are important in the understanding of the passage of human pathogens through the acid of the stomach; an…

Epigenetics pertains to the development of an organism from an undifferential cell, resulting in the successive formation and development of organs and parts that did not pre-exist in the fertilized egg. An exciting and stimulating volume which used …

Examines the establishment of the germ layers and other cell lineages in the early embryo including details of cell movements during the beginning stages of primitive streak formation. Discusses patterns of gene expression during the development of s…

The field of neural transplantation is at a crucial stage, with important clinical trials on transplantation in patients with Parkinson's disease nearing completion and novel, alternative approaches to fetal transplantation being developed. This time…

Details the application of positron emission tomography (PET) to the mapping of human cerebral cortical function. Coverage includes all aspects of PET technology. Includes chapters on somatosensory, motor and visual systems, and higher-order processe…

Both timely and topical, this book examines the most important aspects of the relationship between alcohol consumption and health. Drawing together much new and exciting work in this area, it reviews this emotive subject from a dispassionate perspect…

Antibiotic Resistance: Origins, Evolution, Selection and Spread Chairman: Stuart B. Levy, 1997 Over the last 50 years, the rapid increase in the use of antibiotics, not only in people, but also in animal husbandry and agriculture, has delivered a sel…

ATP, the intracellular energy source, is also an extremely important cell–cell signalling molecule for a wide variety of cells across evolutionarily diverse organisms. The extracellular biochemistry of ATP and its derivatives is complex, and the mult…

Prestigious contributors summarize current knowledge regarding the biosynthesis of tetrapyrrole pigments–chlorophyll, haem, vitamin B12. Describes the structure and regulation of key enzymes along with various pathways, molecular genetic studies and …

How the amino acid sequence of a protein determines its three-dimensional structure is a major problem in biology and chemistry. Leading experts in the fields of NMR spectroscopy, X-ray crystallography, protein engineering and molecular modeling offe…

Using a multidisciplinary approach, it combines anatomical, cellular and physiological studies by preeminent experts. Features important insights into the function of the hypothalamus.

Insect-Plant Interactions and Induced Plant Defence Chair: John A. Pickett, 1999 This book examines the sophisticated mechanisms that plants use to defend themselves against attack by insects and pathogens, focusing on the networks of plant signallin…

The molecular mechanisms and protein species associated with the mineralization of mature dental enamel are active areas of research. This book focuses on specific areas of research including the structural chemistry, protein biochemistry and genetic…