Derek J. Chadwick

Drawing together contributions from a diverse group of international experts in the field, this collection of papers examines the biology and pathology of elastin at the molecular level. Topics include the structure, ultrastructure and function of el…

Gramicidin channels have been studied intensively for more than 25 years. They serve as model transport systems for large protein ion channels, since it is difficult to glean high-resolution structural information on the latter. This book includes co…

Details the application of positron emission tomography (PET) to the mapping of human cerebral cortical function. Coverage includes all aspects of PET technology. Includes chapters on somatosensory, motor and visual systems, and higher-order processe…

Smooth muscle contraction is a vital component of the functioning of blood vessels, the uterus, airways and the bladder. Its malfunction can lead to serious pathological conditions, such as hypertension and pre-term labour. The calcium ion plays a ce…

T cells are a specialized population of immune cells that aid the immune system in combating various types of invading pathogens. This book presents up-to-the-minute data on the role of T cells in autoimmune diseases.

Cl- absorption and HCO3- secretion are intimately associated processes vital to epithelial function, itself a key physiological activity. Until recently the transporters responsible remained obscure, but a breakthrough occurred with the discovery of …

The mapping of human genes is proceeding rapidly. Genes associated with specific inherited diseases are being identified, often providing insight into the molecular cause of the disease. At the moment, however, little consideration is being given to …

Prestigious contributors describe the genetic, molecular, anatomical and neurochemical mechanisms and pathways that operate to regulate and control circadian rhythmicity and functioning in organisms ranging from unicellular algae to human beings. Als…

Although normally thought of as a sex hormone, recent research has highlighted the numerous and significant effects that oestrogen has on the CNS, extending far beyond its important reproductive role. It has been shown that oestrogen acts as a neural…

Prestigious contributors summarize current knowledge regarding the biosynthesis of tetrapyrrole pigments–chlorophyll, haem, vitamin B12. Describes the structure and regulation of key enzymes along with various pathways, molecular genetic studies and …

Recent application of the techniques of molecular biology and patch-clamp physiology has led to rapid advances in understanding the molecular events in chemosensory transduction. In this book, the latest results are presented and discussed by leading…

This volume examines obesity disorders which can lead to diabetes, hypertension and hyperlipidaemia. It offers an interdisciplinary and international look at all aspects of the origins, consequences and treatment of obesity.

Smooth muscle contraction is a vital component of the functioning of blood vessels, the uterus, airways and the bladder. Its malfunction can lead to serious pathological conditions, such as hypertension and pre-term labour. The calcium ion plays a ce…

Part of the prestigious Novartis Foundation series, this volume uniquely addresses the use of innate immunity to treat or prevent infectious diseases of the lung. Innate Immunity to Pulmonary Infection: Provides a comprehensive overview of pulmonary …

The field of neural transplantation is at a crucial stage, with important clinical trials on transplantation in patients with Parkinson's disease nearing completion and novel, alternative approaches to fetal transplantation being developed. This time…

Working on Corticotropin-Releasing Factor in a variety of systems, experts present a coherent depiction of this peptide's role in the control and coordination of the response to stress-inducing situations.

The recent identification of susceptibility genes for schizophrenia, depression and learning and memory dysfunction suggest that psychiatric disorders may be influenced by a small number of genes with multiple actions. This is the first book to inves…

ATP, the intracellular energy source, is also an extremely important cell–cell signalling molecule for a wide variety of cells across evolutionarily diverse organisms. The extracellular biochemistry of ATP and its derivatives is complex, and the mult…

Insect-Plant Interactions and Induced Plant Defence Chair: John A. Pickett, 1999 This book examines the sophisticated mechanisms that plants use to defend themselves against attack by insects and pathogens, focusing on the networks of plant signallin…

A compilation of articles by prominent experts in their respective fields on compensation for and collaboration with indigenous people in regard to their knowledge and provision of rare plants which are used for some of the most potent drugs in Weste…