Gregory R. Bock

The term «unconventional virus» refers to virus-like agents that differ from conventional viruses in significant respects–resistance to agents that inactivate normal viruses, for example. Certain rare and fatal neurological disorders, such as the Cre…

Parkinson's disease, Alzheimer's disease, and motor neuron disease share a significant common feature: selective death of neurons in restricted regions of the brain. This international symposium, held by the Ciba Foundation in 1986, is the first to b…

Amyloid fibrils are associated with a range of pathological disorders including Alzheimer's Disease, Down's syndrome, diabetes, cardiomyopathies, and transmissible spongiform encephalopathies. This volume is a comprehensive account of recent developm…

Over recent decades vast amounts of biological data have been accumulated. However, it is becoming increasingly difficult to apply traditional theoretical methods to the formulation of coherent pictures of cell and organ function because it is no lon…

To understand the brain and its devastating diseases, we need to reveal the mechanisms that produce it and the ways in which it can constantly change throughout a lifetime. This book features a timely and insightful discussion between developmental n…

'Homology' as a concept became increasingly elusive during the course of the 20th century. The central debates and controversies concern both fundamental definitions and the nature of the criteria by which homology is judged. Attempts to move away fr…

Written for psychologists, educational psychologists and developmental biologists, this volume explores the concept of giftedness, including its definition, origins and development. The author offers a balanced view of the topic and presents optimal …

Neural tube defects are the second most common cause of perinatal death from birth defects in the United Kingdom. In this important book, leading scientists evaluate the latest evidence on the causative factors–both genetic and environmental–of these…

The potential lipotoxic effect of accumulation of fatty acids in non-adipose tissues is thought to be a major component in the development of insulin resistance. Chronic exposure to high concentrations of free fatty acids in the blood affects pancrea…

An invaluable book containing a series of interdisciplinary discussions between clinical and basic scientists. Biology of IGF-1: Its interaction with insulin and health and malignant states focuses on key issues such as: the definition of danger zone…

Understanding stem cells at the molecular level is essential to understanding their behaviour in a physiological context. This volume in our acclaimed Novartis Foundation series features animated discussion from the world’s experts in this topic on t…

Over the last several years, immunologists have re-discovered the importance of regulatory lymphocytes, formerly termed 'suppressor cells'. Many recent reports have documented their existence, effector functions and potential therapeutic benefits in …

This book features scientists from a broad spectrum of disciplines discussing recent data on aggression in laboratory animals with particular reference to possible implications for understanding human aggression. Chapters focus on the major current e…

Tissue engineering takes advantages of the combined use of cultured living cells and three-dimensional scaffolds to reconstruct adult tissues that are absent or malfunctioning. This book brings together scientists and clinicians working on a variety …

Epithelial cells cover the outer and inner surfaces of the body, forming a selective polarized barrier between the intercellualar space and the 'external' world. Linking the cells of this continuous layer and contributing to epithelial organization a…

Modern technology has made possible epidemiological studies that relate aspects of neonatal health to disease in adult life. This symposium is the first to draw together information from this new research area. Explores links between early growth and…

Ciba Foundation Symposium 123 Antidepressants and Receptor Function Chairman: Dennis Murphy, 1986 Depression is a common and often debilitating affective disorder. Attempts to develop effective antidepressants have a long history, but many questions …

Anaphylaxis is an immediate-type allergic reaction involving the whole organism. It is the most life-threatening allergic condition. Although there are few exact epidemiological data regarding prevalence, estimates regarding insect sting anaphylaxis …

Cigarette smoking is estimated to lead to 4.9 million premature deaths per year worldwide. This is predicted to rise to 10 million by 2020. In western countries it kills half of all smokers who fail to stop. The prevailing model for tobacco addiction…