Jamie A. Goode

A comprehensive volume examining the fundamental questions raised by reductionists' theory about levels of explanation necessary to understand biological systems. The book evaluates the enormously powerful techniques of molecular biology, and analyze…

Understanding stem cells at the molecular level is essential to understanding their behaviour in a physiological context. This volume in our acclaimed Novartis Foundation series features animated discussion from the world’s experts in this topic on t…

Retinal dystrophies are the major causes of incurable blindness in the Western world. Our insight into their aetiology has improved remarkably over the past decade and a number of key genes have been identified. Together with a more detailed understa…

Much recent research in evolutionary developmental biology has focused on the origin of new body plans. However, most evolutionary change at the population and species level consists of tinkering: small-scale alterations in developmental pathways wit…

This book explores the possibility that life exists on Mars. It provides an interdisciplinary overview of the early evolution of life in hydrothermal ecosystems on Earth, focusing on the problem of remote sensing and incorporating geological work rel…

Cl- absorption and HCO3- secretion are intimately associated processes vital to epithelial function, itself a key physiological activity. Until recently the transporters responsible remained obscure, but a breakthrough occurred with the discovery of …

This book is a comprehensive and up-to-date account of where we stand in immunological strategies for preventing or treating type 1 diabetes (T1D). Brings together contributions from the leaders in the arena of clinical immunotherapy, not limited to …

The field of lymphokine research has grown in parallel to the exciting developments around the two sets of cells which defend the body. While lymphokines are the «property» of immunologists, the molecular regulators of hemopoiesis (CSFs) belong to th…

A timely volume dealing with the evolutionary and structural links between the clotting and fibrinolytic proteins and plasminogen-related growth factors. The role of individual domains for enzymatic proteins and plasminogen-related growth factors is …

Osteoarthritis is a chronic degenerative disease associated with joint pain and loss of joint function. It has an estimated incidence of 4 out of every 100 people and significantly reduces the quality of life in affected individuals. The major sympto…

This book brings together material on all aspects of immunological tolerance. Basic mechanisms of tolerance are examined in detail, including mechanisms of peripheral T cell tolerance, molecular and genetic mechanisms for maintaining self tolerance, …

This book offers a fresh perspective on the controversial topic of criminal and antisocial behavior. It synthesizes findings from behavioral and population genetics, evolutionary biology and criminology and presents the latest findings in twin studie…

Dietary supplements can contain a wide variety of ingredients, either singly or in combination, including nutrients, botanicals and 'bioactive components' commonly found in foods. They are marketed and used by consumers for a range of reasons: to enh…

Dengue virus is a member of the Flaviviridae family, which includes viruses associated with human diseases such as yellow fever, Japanese encephalitis and hepatitis C. Dengue fever is transmitted by mosquitoes, principally Aedes aegypti. There are fo…

Both timely and topical, this book examines the most important aspects of the relationship between alcohol consumption and health. Drawing together much new and exciting work in this area, it reviews this emotive subject from a dispassionate perspect…

The formation of blood vessels is an essential aspect of embryogenesis in vertebrates. It is a central feature of numerous post-embryonic processes, including tissue and organ growth and regeneration. It is also part of the pathology of tumour format…

This title provides an extremely helpful analysis of genes that may be associated with autoimmunity, and answers questions such as how these genes can be identified, and how the functions of the gene products can be elucidated. Incorporating data on …

Brings together key new results of interdisciplinary collaborations among various research fields on rhodopsin including the photoreceptive mechanism of rhodopsins, the molecular mechanism of the visual transduction process, visual processes in the r…