Stressing strategic and technological solutions to medicinal chemistry challenges, this book presents methods and practices for optimizing the chemical aspects of drug discovery. Chapters discuss benefits, challenges, case studies, and industry perspectives for improving drug discovery programs with respect to quality and costs. • Focuses on small molecules and their critical role in medicinal chemistry, reviewing chemical and economic advantages, challenges, and trends in the field from industry perspectives • Discusses novel approaches and key topics, like screening collection enhancement, risk sharing, HTS triage, new lead finding approaches, diversity-oriented synthesis, peptidomimetics, natural products, and high throughput medicinal chemistry approaches • Explains how to reduce design-make-test cycle times by integrating medicinal chemistry, physical chemistry, and ADME profiling techniques • Includes descriptive case studies, examples, and applications to illustrate new technologies and provide step-by-step explanations to enable them in a laboratory setting 


химия

химия полимеров

Small Molecule Medicinal Chemistry. Strategies and Technologies

любовные романы

фэнтези

учебная и научная литература

современная русская литература

современные любовные романы

современная зарубежная литература

детективы

об истории серьезно

приключения

книги о приключениях

ужасы / мистика

учебники и пособия для вузов

cтихи, поэзия

книги по психологии

стихи и поэзия

гуманитарные и общественные науки

русская классика

мистика

боевики, остросюжетная литература

публицистическая литература

Leading in a Culture of Change: Personal Action Guide and Workbook is an essential companion to Michael Fullan's bestselling book, Leading in a Culture of Change. This practical guide is designed to help leaders in all sectors (corporate, education, public, and nonprofit) manage and drive productive change within their organizations. The workbook is filled with illustrative case examples, exercises, and resources that you can use with individuals or groups. It will help you (and any change agent) integrate the five core competencies—attending to a broader moral purpose, keeping on top of the change process, cultivating relationships, sharing knowledge, and setting a vision and context for creating coherence in organizations—and empower you to deal with the issues of complex change. 

зарубежная деловая литература

Leading in a Culture of Change Personal Action Guide and Workbook

For the first time ever, Margaret Lomas has combined all her positive cash flow property strategies into a step-by-step manual to guide new investors through the processes of establishing a property portfolio. Inside you will learn: Where to look for positive cash flow property The contracts you need to understand The process of applying for finance How to choose a property manager Methods to prepare for tax How to manage a property sale. Positive cash flow properties will put money in your pocket each week and can set you on the path to financial freedom. Margaret has included checklists and practical worksheets to guide you along the road one step at a time.

личные финансы

A Pocket Guide to Investing in Positive Cash Flow Property

When it comes to buying and selling real estate, knowledge is power – and this book lets you in on the secrets. Everything You Need to Know (But Forget to Ask) When Buying or Selling Property is a concise, authoritative guide. In plain, simple language, real estate agent Mary Smits looks at the many issues that confront both buyers and sellers, including: choosing a home or investment property wisely negotiating to save money understanding the paperwork dealing with and choosing real estate agents preparing to sell your property moving home. Mary explains how to search for property on the internet and provides tips to help you use buying and selling tactics to your advantage and avoid potential traps. The book features useful check lists to take with you to inspections, along with sound, practical advice.

недвижимость

Everything You Need to Know (But Forget to Ask) When Buying or Selling Property

Get to know what Formula One racing is all about This book delves into the strategy, technology, and spirit needed to win a Formula One race. Every angle of a race weekend is covered in detail, from scrutineering to pitstops to podium. You’ll also read about the rivalries and politics that have turned the sport into a global televised drama. Illustrated with black and white photographs, Formula One Racing For Dummies will serve the die-hard spectator or armchair fan alike. Discover how to: Identify race strategies Understand the role of each team member Master the latest rules and regulations Appreciate a Formula One car’s cutting-edge design Enjoy Formula One from the stands and on TV The Dummies Way Explanations in plain English «Get in, get out» information Icons and other navigational aids Tear-out cheat sheet Top ten lists A dash of humour and fun 

спорт / фитнес

хобби / увлечения

спорт

Formula One Racing For Dummies

An easy-to-follow guide to a hot new form of yoga Yoga with Weights is the latest breakthrough in mind-body exercise, integrating the mindfulness of yoga with the physical culture of body-building. Building on the strengths of both disciplines, this friendly guide shows readers how to safely combine yoga postures while simultaneously working out with lightweight hand-held free weights. It features customizable exercises that target specific areas of the body, each illustrated with multiple photos, and provides guidelines for combining healthy eating with workouts. Sherri Baptiste (Marin County, CA) is the founder of Baptiste Power of Yoga, a nationally recognized method of yoga offered throughout the United States. She teaches yoga classes throughout the United States and hosts retreats around the world.

йога

Yoga with Weights For Dummies

The definitive look at Wall Street in the 19th Century Perhaps the 19th century's best book on Wall Street, Fifty Years in Wall Street provides a fascinating look at the financial markets during a period of rapid economic expansion. Henry Clews was a giant figure in finance at that time, and his firsthand account brings this colorful era to life like never before. He reveals shocking stories of political and economic manipulation and how he helped bring down the mighty Boss Tweed. He writes eloquently about the madness of the markets and how the era's greatest speculators amassed their fortunes. This book provides an expansive view of Wall Street in an era of little regulation, rampant political corruption, and rapid financial change. Henry Clews was born in England in 1836 and emigrated to the United States in 1850. In 1859, he cofounded what became the second largest marketer of federal bonds during the Civil War. Later, he organized the «Committee of 70,» which deposed the corrupt Tweed Ring in New York City, and served as an economic consultant to President Ulysses Grant.

корпоративные финансы

финансовый менеджмент

Fifty Years in Wall Street

A complete guide to planning an estate under today's tax rules When it comes to your estate–no matter how big or small it may be–you shouldn't leave anything to chance. Proper planning is necessary to protect both your assets and your heirs. Estate Planning Law Specialist Harold Apolinsky and expert financial planner Stewart Welch III know this better than anyone else, and in the Revised and Updated Edition of J.K. Lasser's New Rules for Estate and Tax Planning, they offer valuable advice and solid strategies to help you plan your estate under today's tax rules as well as preserve your wealth. Packed with up-to-the-minute facts, this practical resource covers important issues, such as: * How new legislation will impact inheritances and trusts * Estate and generation-skipping tax planning * The role of wills, executors, and trusts * Treatment of charitable contributions * The do's and don'ts of gifting * Life insurance and retirement planning Filled with in-depth insights and expert advice, this book will show you how to efficiently arrange your estate today so that you can leave more to those you care about tomorrow. 

J.K. Lasser's New Rules for Estate and Tax Planning

Полная версия

Small Molecule Medicinal Chemistry. Strategies and Technologies