#189 – David Sinclair: Extending the Human Lifespan Beyond 100 Years

David Sinclair is a geneticist at Harvard and author of Lifespan. Please support this podcast by checking out our sponsors: - Onnit: lexfridman.com/onnit to get up to 10% off - Clear: clearme.com/lexpod and use code LexPod to get 2 months free - National Instruments (NI): ni.com/perspectives - SimpliSafe: simplisafe.com/lex and use code LEX to get a free security camera - Linode: linode.com/lex to get $100 free credit EPISODE LINKS: David's Twitter: twitter.com/davidasinclair David's Website: lifespanbook.com PODCAST INFO: Podcast website: lexfridman.com/podcast Apple Podcasts: apple.co/2lwqZIr Spotify: spoti.fi/2nEwCF8 RSS: lexfridman.com/feed/podcast/ YouTube Full Episodes: youtube.com/lexfridman YouTube Clips: youtube.com/lexclips SUPPORT & CONNECT: - Check out the sponsors above, it's the best way to support this podcast - Support on Patreon: patreon.com/lexfridman - Twitter: twitter.com/lexfridman - Instagram: instagram.com/lexfridman - LinkedIn: linkedin.com/in/lexfridman - Facebook: facebook.com/lexfridman - Medium: medium.com/@lexfridman OUTLINE: Here's the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) - Introduction (09:34) - Staying young at heart (13:31) - Bringing people back to life (19:05) - Wearables and tracking health data (28:18) - How to solve aging (38:23) - Why do we age? (43:50) - Genetic reset switch that reverses aging (46:20) - AI in biology (48:52) - Health data (56:58) - Fasting (1:04:29) - Diet (1:12:41) - Exercise (1:18:01) - Sleep (1:26:29) - Data (1:32:00) - Extending lifespan (1:34:42) - Immortality (1:40:28) - Denial of death (1:43:45) - Meaning of life without death