Gail Cardew

This book describes a diverse analysis of the five somatostatin receptors; somatostatin gene regulation; promatostatin processing; mechanisms of signal transduction; and the design and use of somatostatin analogues, including their possible clinical …

'Homology' as a concept became increasingly elusive during the course of the 20th century. The central debates and controversies concern both fundamental definitions and the nature of the criteria by which homology is judged. Attempts to move away fr…

The use of oligonucleotides as therapeutic agents rests upon their ability to interfere, in a sequence-specific manner, with the fundamental machinery of protein synthesis either by binding to the mRNAs transcribed from a gene or by binding directly …

This volume examines obesity disorders which can lead to diabetes, hypertension and hyperlipidaemia. It offers an interdisciplinary and international look at all aspects of the origins, consequences and treatment of obesity.

The molecular mechanisms and protein species associated with the mineralization of mature dental enamel are active areas of research. This book focuses on specific areas of research including the structural chemistry, protein biochemistry and genetic…

Epigenetics pertains to the development of an organism from an undifferential cell, resulting in the successive formation and development of organs and parts that did not pre-exist in the fertilized egg. An exciting and stimulating volume which used …

This book contains chapters by some of the leading figures in the field of evolutionary psychology. The latest data are presented on evolutionary theories in perception, information, various aspects of social behaviour, language, learning and aggress…

T cells are a specialized population of immune cells that aid the immune system in combating various types of invading pathogens. This book presents up-to-the-minute data on the role of T cells in autoimmune diseases.

The mapping of human genes is proceeding rapidly. Genes associated with specific inherited diseases are being identified, often providing insight into the molecular cause of the disease. At the moment, however, little consideration is being given to …

This new work contains the first integrated discussion of the role of olfaction in mosquito-host interactions. It covers the practical applications of this knowledge in attempting to control malaria as a problem for world health. The volume begins wi…

Asthma is a growing health problem throughout the developed world. This volume presents a critical review of all the possible factors for this rising trend and includes research that has not yet been published in the scientific literature. Discusses …

Gap junctions are key elements in communication between cells in multicellular organisms. It is clear that their activity is essential for normal embryonic development and normal function in adult organs, although the individual roles of the proteins…

Gramicidin channels have been studied intensively for more than 25 years. They serve as model transport systems for large protein ion channels, since it is difficult to glean high-resolution structural information on the latter. This book includes co…

Telomeres and Telomerase Chairman: Sydney Brenner, 1997 Telomeres are the protective genetic elements located at the ends of chromosomes and are essential for correct chromosomal structure and function. They are not fully replicated by the convention…

There is an urgent need to uncover new therapies that will protect against malaria, as the parasite becomes increasingly resistant to available drugs and this book offers insights into three interrelated aspects of the malaria-infected erythrocyte: *…

This up-to-the-minute account examines how radionuclides affect human health. It explores how radionuclides travel through various food chains and how they are transported throughout the terrestrial and aquatic environments.

Microbial responses to acidic and alkaline pH are important in many areas of bacteriology. For example, the mechanisms of resistance to acidic pH are important in the understanding of the passage of human pathogens through the acid of the stomach; an…